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Article

[HLA-DRB1 typing in Caucasians patients with neuromyelitis optica].

Revista de neurologia - 1 Aug 2011

Blanco Y, Ercilla-González G, Llufriu S, Casanova-Estruch B, Magraner M J, Ramió-Torrentá Ll, Mendibe-Bilbao M M, Uclés-Sánchez A J, Casado-Chocán J L, López de Munain A, Ramo-Tello C, Santos-Lasaosa S, Fernández-Bolaños Porras R, Segura-Bruna N, Sepulveda-Gázquez M, Villoslada P, Graus F, Saiz A

Abstract excerpt

INTRODUCTION: The existence of antibodies to aquaporin-4 (AQP-4-ab) has identified neuromyelitis optica (NMO) and multiple sclerosis (MS) as different diseases. Although HLA-DRB1 alleles contribute to MS risk, recent studies suggest that HLA back-ground differs between patients with NMO or MS in non-Caucasians populations. Our study was aimed to analyze HLA-DRB1 distribution in Caucasians NMO patients. SUBJECTS...

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PMID: 21748712

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