Article
NRAMP1 (SLC11A1) variants: genetic susceptibility to multiple Sclerosis.
Journal of clinical immunology - 1 Jul 2010
Ates Omer, Kurt Semiha, Bozkurt Nihan, Karaer Hatice
Abstract excerpt
OBJECTIVES: Multiple sclerosis (MS) is an inflammatory, autoimmune demyelinating disease of the central nervous system. Human Natural Resistance Associated Macrophage Protein 1 (NRAMP1) gene polymorphisms have been implicated in the immune mediated diseases susceptibility. This study aimed to investigate the plausible association between NRAMP1 gene and MS susceptibility. METHODS: We analyzed (GT)(n,) INT4, 3'UTR...
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