The Role of HLA in MS Susceptibility and Phenotype.

doi:10.1007/7854_2014_357

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Article

The Role of HLA in MS Susceptibility and Phenotype.

Current topics in behavioral neurosciences - 1 Jan 2015

Greer Judith M

Abstract excerpt

One of the most consistent findings in multiple sclerosis (MS) is that development of MS is linked with carriage of the class II human leucocyte antigen (HLA) molecule HLA-DRB1*15:01; around 60 % of Caucasian MS patients carry this allele compared to 25-30 % of ethnically matched healthy individuals. However, other HLA molecules have also been linked to the development of MS. In this chapter, the association...

Topics

Disease Susceptibility
Genetic Predisposition to Disease
HLA Antigens
Humans
Multiple Sclerosis
Phenotype

Source

Open in PubMed

Identifiers

PMID: 25502788
DOI: 10.1007/7854_2014_357

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