Article
HLA associations with multiple sclerosis in Greece.
Journal of the neurological sciences - 15 Sept 2011
Kouri Ioanna, Papakonstantinou Stylianos, Bempes Vaios, Vasiliadis Haris S, Kyritsis Athanasios P, Pelidou Sygkliti-Henrietta
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is a demyelinating inflammatory disease of the central nervous system originated by a complex interplay of environmental and genetic factors. The association of MS with the human leukocyte antigen (HLA) class II alleles was investigated in MS patients in northwest Greece, in the geographical region of Epirus. OBJECTIVE: Our aim was to estimate the prevalence of the...
Topics
- Adult
- Aged
- Female
- Gene Expression Profiling
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Greece
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DRB1 Chains
- Haplotypes
- Humans
- Male
- Middle Aged
- Multiple Sclerosis
- Young Adult
