Article
HLA class II polymorphism in Latin American patients with multiple sclerosis.
Autoimmunity reviews - 1 Apr 2010
Rojas Olga-Lucía, Rojas-Villarraga Adriana, Cruz-Tapias Paola, Sánchez Jorge Luis, Suárez-Escudero Juan-Camilo, Patarroyo Manuel-Alfonso, Anaya Juan-Manuel
Abstract excerpt
OBJECTIVE: To identify HLA-DRB1 alleles contributing to susceptibility to multiple sclerosis (MS) in a Colombian population and to estimate the common effect size of HLA class II on MS susceptibility in Latin American populations through a meta-analysis. METHODS: A total of 65 Colombian patients with MS and 184 matched controls were included. HLA-DRB1 typing was done using the sequence-specific oligonucleotide...
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