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Article

Combination of Myelin Basic Protein Gene Polymorphisms with HLA-DRB1*1501 in Iranian Patients with Multiple Sclerosis.

Iranian journal of immunology : IJI - 1 Sept 2017

Nejati Parham, Attar Marzieh, Rahimian Maryam, Fathi Davood, Shahbazi Majid

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS), as a multifactorial autoimmune disease with complex genetic basis, causes demyelination in the central nervous system via cytokine responses to myelin antigens. Myelin basic protein (MBP) is the main protein component of the myelin sheath. HLA-DRB (human leukocyte antigen-DR beta) alleles, particularly HLA-DRB1*1501, may be of significance in the pathogenesis of MS. OBJECTIVE:...

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Identifiers

PMID: 28919586
DOI: 10.22034/iji.2017.39313

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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