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Article

Analysis of ICAM1 gene polymorphism in Slovak multiple sclerosis patients.

Folia microbiologica - 1 Jul 2017

Shawkatová Ivana, Javor Juraj, Párnická Zuzana, Bucová Mária, Čopíková-Cudráková Daniela, Michalík Jozef, Gmitterová Karin, Čierny Daniel, Buc Milan, Ďurmanová Vladimíra

Abstract excerpt

Infiltration of immune cells into CNS is one of the essential events in multiple sclerosis (MS) development. Adhesion molecules like the intercellular adhesion molecule 1 (ICAM-1) play critical role in this process. Therefore, the ICAM1 gene containing two important single-nucleotide polymorphisms (SNPs) belongs to candidate loci with possible involvement in MS susceptibility and/or severity. The objective of our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28130760
DOI: 10.1007/s12223-017-0499-6

Genes

ICAM1

Variants

rs1799969
rs1799969

Provenance

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