Article
Ubiquitous polygenicity of human complex traits: genome-wide analysis of 49 traits in Koreans.
PLoS genetics - 1 Jan 2013
Yang Jian, Lee Taeheon, Kim Jaemin, Cho Myeong-Chan, Han Bok-Ghee, Lee Jong-Young, Lee Hyun-Jeong, Cho Seoae, Kim Heebal
Abstract excerpt
Recent studies in population of European ancestry have shown that 30% ~ 50% of heritability for human complex traits such as height and body mass index, and common diseases such as schizophrenia and rheumatoid arthritis, can be captured by common SNPs and that genetic variation attributed to chromosomes are in proportion to their length. Using genome-wide estimation and partitioning approaches, we analysed 49...
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