Article
Phenome-wide heritability analysis of the UK Biobank.
PLoS genetics - 1 Apr 2017
Ge Tian, Chen Chia-Yen, Neale Benjamin M, Sabuncu Mert R, Smoller Jordan W
Abstract excerpt
Heritability estimation provides important information about the relative contribution of genetic and environmental factors to phenotypic variation, and provides an upper bound for the utility of genetic risk prediction models. Recent technological and statistical advances have enabled the estimation of additive heritability attributable to common genetic variants (SNP heritability) across a broad phenotypic...
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