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Article

Genome-wide association studies for common diseases and complex traits.

Nature reviews. Genetics - 1 Feb 2005

Hirschhorn Joel N, Daly Mark J

Abstract excerpt

Genetic factors strongly affect susceptibility to common diseases and also influence disease-related quantitative traits. Identifying the relevant genes has been difficult, in part because each causal gene only makes a small contribution to overall heritability. Genetic association studies offer a potentially powerful approach for mapping causal genes with modest effects, but are limited because only a small...

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PMID: 15716906
DOI: 10.1038/nrg1521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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