Article
Human leukocyte antigen class I alleles and haplotypes associated with primary hepatocellular carcinoma in persistent HBV-infected patients.
Human immunology - 1 Jun 2013
Pan Ning, Chen Keping, Qiu Jie, Sun Hang, Xu Jinhuan, Miao Fengqin, Shi Qian, Jiang Wei, Jin Hui, He Youji, Xie Wei, Zhang Jianqiong
Abstract excerpt
Many studies have shown that Human leukocyte antigen (HLA) class I alleles are associated with the development of various cancers. However, its role in hepatocellular carcinoma (HCC) is still unknown. To investigate whether HLA class I allelic polymorphism is related to the development of hepatitis B virus(HBV)-associated HCC, a total of 326 HBV-infected patients (138 individuals with HCC and 188 well-matched...
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