Article
Human leukocyte antigen class I alleles and haplotypes associated with primary hepatocellular carcinoma in persistent HBV-infected patients.
Human immunology - 1 Jun 2013
Pan Ning, Chen Keping, Qiu Jie, Sun Hang, Xu Jinhuan, Miao Fengqin, Shi Qian, Jiang Wei, Jin Hui, He Youji, Xie Wei, Zhang Jianqiong
Abstract excerpt
Many studies have shown that Human leukocyte antigen (HLA) class I alleles are associated with the development of various cancers. However, its role in hepatocellular carcinoma (HCC) is still unknown. To investigate whether HLA class I allelic polymorphism is related to the development of hepatit...
Topics
- Adult
- Alleles
- Carcinoma, Hepatocellular
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Haplotypes
- Hepatitis B virus
- Hepatitis B, Chronic
- Histocompatibility Antigens Class I
- Humans
- Liver Cirrhosis
- Liver Neoplasms