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Article

Differential localization of T-bet and Eomes in CD8 T cell memory populations.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2013

McLane Laura M, Banerjee Pinaki P, Cosma Gabriela L, Makedonas George, Wherry E John, Orange Jordan S, Betts Michael R

Abstract excerpt

In mice, two T-box transcription factors, T-box expressed in T cells (T-bet) and eomesodermin (Eomes), drive the differentiation of CD8 T cell lineages; however, little is known regarding their role in human CD8 T cell differentiation. In this study, we characterized T-bet and Eomes expression and localization within human CD8 memory T cell populations. We find that T-bet and Eomes are broadly expressed in human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23455505
DOI: 10.4049/jimmunol.1201556
PMCID: PMC3608800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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