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Article

Infection History Determines the Differentiation State of Human CD8 <sup>+</sup> T Cells

26 Feb 2015

Abstract excerpt

UNLABELLED: After the resolution of the acute phase of infection, otherwise quiescent antigen-experienced CD8(+) T cells confer rapid protection upon reinfection with viral pathogens or, in the case of persistent viruses, help to maintain control of the infection. Depending on the type of virus, antigen-specific CD8(+) T cells have distinct traits, ranging from typical memory cell properties in the case of...

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PMID: 25717102
DOI: 10.1128/jvi.03478-14

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