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Article

Role of interstitial inflammation in the pathogenesis of polycystic kidney disease.

Nephrology (Carlton, Vic.) - 1 May 2013

Ta Michelle H T, Harris David C H, Rangan Gopala K

Abstract excerpt

Interstitial infiltrates, consisting of macrophages and other inflammatory cells, have been consistently reported in human and animal models of polycystic kidney diseases (PKD). However, the mechanisms underlying this inflammation are not well defined. Evidence suggests that interstitial inflammation in PKD is driven by pro-inflammatory chemoattractants such as monocyte chemoattractant protein-1 (MCP-1), and...

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PMID: 23448509
DOI: 10.1111/nep.12045

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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