Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NLRP2 Regulates Proinflammatory and Antiapoptotic Responses in Proximal Tubular Epithelial Cells

24 Oct 2019

Abstract excerpt

Nod-like Receptor Pyrin domain containing proteins (NLRPs) expressed by resident renal cells may contribute to the pathogenesis of multiple renal diseases. Cystinosis is a genetic disorder that affects kidney and particularly proximal tubular epithelial cells (PTEC). Here, we investigated the expression of NLRP family members in human control and cystinotic conditionally immortalized PTEC. Among all the NLRPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Research and Pathophysiology
Share to Erythrocyte Function and Pathophysiology
Share to Skin Diseases and Diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31709256
DOI: 10.3389/fcell.2019.00252

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NLRP2 Regulates Proinflammatory and Antiapoptotic Responses in Proximal Tubular Epithelial CellsPMID 31709256Read ↗

The role of NLRP12 in inflammatory diseasesSemantic proximity Read ↗

NLRP2 in health and diseaseSemantic proximity Read ↗

Inflammasome-Independent NLRP3 Augments TGF-β Signaling in Kidney EpitheliumSemantic proximity Read ↗

Role of Inflammasomes in Kidney Diseases via Both Canonical and Non-canonical PathwaysSemantic proximity Read ↗

Nephropathic Cystinosis: Pathogenic Roles of Inflammation and Potential for New TherapiesSemantic proximity Read ↗

The NLR family pyrin domain-containing 11 protein contributes to the regulation of inflammatory signaling.Semantic proximity Read ↗

NLRP2, an inhibitor of the NF-kappaB pathway, is transcriptionally activated by NF-kappaB and exhibits a nonfunctional allelic variant.Semantic proximity Read ↗

Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung DiseaseSemantic proximity Read ↗

The Role of NLRP3 Inflammasome in Lupus Nephritis.Semantic proximity Read ↗

A Genome-Wide siRNA Screen Reveals Positive and Negative Regulators of the NOD2 and NF-κB Signaling PathwaysSemantic proximity Read ↗

NLRP3 Localizes to the Tubular Epithelium in Human Kidney and Correlates With Outcome in IgA Nephropathy.Semantic proximity Read ↗

NLR functions beyond pathogen recognition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.