Article

The renal inflammatory network of nephronophthisis

2021-01-08

Abstract excerpt

<h4>STRUCTURED ABSTRACT</h4> <h4>BACKGROUND</h4> The majority of genetic kidney disease leading to kidney failure is caused by mutations in ciliary genes. How cilia malfunction leads to progressive kidney damage is poorly understood, but recent evidence links ciliopathy genes to CCL2 dependent macrophage recruitment in autosomal dominant polycystic kidney disease (ADPKD), the most studied renal ciliopathy. Wheth...

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Literature Corpus work: 7cbef112-b217-5f71-8c40-50a5438b8d9b
DOI: 10.1101/2021.01.07.425719

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