Article
Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56,307 individuals from the HUNT study in Norway.
European journal of human genetics : EJHG - 1 Nov 2013
Gabrielsen Maiken E, Romundstad Pål, Langhammer Arnulf, Krokan Hans E, Skorpen Frank
Abstract excerpt
Genetic studies have shown an association between single-nucleotide polymorphisms on chromosome 15q25 and smoking-related traits and diseases, such as quantity of smoking, lung cancer and chronic obstructive pulmonary disease (COPD). A discussion has centred on the variants and their effects being directly disease related or indirect via nicotine addiction. To address these discrepancies, we genotyped the...
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