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Article

The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema.

American journal of respiratory and critical care medicine - 1 Mar 2010

Lambrechts Diether, Buysschaert Ian, Zanen Pieter, Coolen Johan, Lays Natacha, Cuppens Harry, Groen Harry J M, Dewever Walter, van Klaveren Rob J, Verschakelen Johny, Wijmenga Cisca, Postma Dirkje S, Decramer Marc, Janssens Wim

Abstract excerpt

RATIONALE: Genome-wide association studies have identified genetic variants in the nicotinic acetylcholine receptor (nAChR) on chromosome 15q24/25 as a risk for nicotine dependence, lung cancer, and chronic obstructive pulmonary disease (COPD). Assessment of bronchial obstruction by spirometry, t...

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Source

Identifiers

PMID: 20007924
DOI: 10.1164/rccm.200909-1364OC

Genes

FEV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20007924-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema.PMID 20007924Read ↗

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