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Article

Flavonoid regulation of EAG1 channels.

The Journal of general physiology - 1 Mar 2013

Carlson Anne E, Brelidze Tinatin I, Zagotta William N

Abstract excerpt

The voltage-gated, K(+)-selective ether á go-go 1 (EAG1) channel is expressed throughout the brain where it is thought to regulate neuronal excitability. Besides its normal physiological role in the brain, EAG1 is abnormally expressed in several cancer cell types and promotes tumor progression. Like all other channels in the KCNH family, EAG1 channels have a large intracellular carboxy-terminal region that shares...

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Identifiers

PMID: 23440277
DOI: 10.1085/jgp.201210900
PMCID: PMC3581696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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