Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Eag1 K+ Channel: Endogenous Regulation and Functions in Nervous System.

Oxidative medicine and cellular longevity - 1 Jan 2017

Han Bo, Tokay Tursonjan, Zhang Guangming, Sun Peng, Hou Shangwei

Abstract excerpt

Ether-à-go-go1 (Eag1, Kv10.1, KCNH1) K+ channel is a member of the voltage-gated K+ channel family mainly distributed in the central nervous system and cancer cells. Like other types of voltage-gated K+ channels, the EAG1 channels are regulated by a variety of endogenous signals including reactive oxygen species, rendering the EAG1 to be in the redox-regulated ion channel family. The role of EAG1 channels in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ether-A-Go-Go Potassium Channels
Share to Mutation
Share to Nervous System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nervous System Diseases

Share to Signal Transduction

Share to Synaptic Transmission

Source

Open in PubMed Open full text

Identifiers

PMID: 28367272
DOI: 10.1155/2017/7371010
PMCID: PMC5358448

Genes

KCNH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Eag1 K+ Channel: Endogenous Regulation and Functions in Nervous System.PMID 28367272Read ↗

[Functional impact of hERG: from physiological role to target of anticancer therapy].Semantic proximity Read ↗

Kv1.1 Channelopathies: Pathophysiological Mechanisms and Therapeutic Approaches.Semantic proximity Read ↗

hERG K(+) channels: structure, function, and clinical significance.Semantic proximity Read ↗

Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implicationsSemantic proximity Read ↗

Kir channels in the CNS: emerging new roles and implications for neurological diseasesSemantic proximity Read ↗

Neuro-bioenergetic concepts in cancer prevention and treatment.Semantic proximity Read ↗

Fentanyl-Induced Block of hERG Channels Is Exacerbated by Hypoxia, Hypokalemia, Alkalosis, and the Presence of hERG1b.Semantic proximity Read ↗

ASIC1a channel in Age-Related Diseases: Therapeutic ImplicationsSemantic proximity Read ↗

Kv10.1 potassium channel: from the brain to the tumorsSemantic proximity Read ↗

Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.Semantic proximity Read ↗

The Functional Properties, Physiological Roles, Channelopathy and Pharmacological Characteristics of the Slack (KCNT1) Channel.Semantic proximity Read ↗

The eag family of K+ channels in Drosophila and mammals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.