Article
Eag1 K+ Channel: Endogenous Regulation and Functions in Nervous System.
Oxidative medicine and cellular longevity - 1 Jan 2017
Han Bo, Tokay Tursonjan, Zhang Guangming, Sun Peng, Hou Shangwei
Abstract excerpt
Ether-à-go-go1 (Eag1, Kv10.1, KCNH1) K+ channel is a member of the voltage-gated K+ channel family mainly distributed in the central nervous system and cancer cells. Like other types of voltage-gated K+ channels, the EAG1 channels are regulated by a variety of endogenous signals including reactive oxygen species, rendering the EAG1 to be in the redox-regulated ion channel family. The role of EAG1 channels in...
Topics
- Animals
- Ether-A-Go-Go Potassium Channels
- Humans
- Mutation
- Nervous System
- Nervous System Diseases
- Signal Transduction
- Synaptic Transmission
