Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance

23 Feb 2013

Abstract excerpt

CONTEXT: Recently irisin (encoded by Fndc5 gene) has been reported to stimulate browning and uncoupling protein 1 expression in sc adipose tissue of mice. OBJECTIVE: The objective of the study was to investigate FNDC5 gene expression in human muscle and adipose tissue and circulating irisin according to obesity, insulin sensitivity, and type 2 diabetes. DESIGN, PATIENTS, AND MAIN OUTCOME MEASURE: Adipose tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Lipid metabolism and biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23436919
DOI: 10.1210/jc.2012-2749

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin ResistancePMID 23436919Read ↗

Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity.Semantic proximity Read ↗

Browning of white fat: does irisin play a role in humans?Semantic proximity Read ↗

Progress and Challenges in the Biology of FNDC5 and IrisinSemantic proximity Read ↗

SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects.Semantic proximity Read ↗

Evidence against a beneficial effect of irisin in humans.Semantic proximity Read ↗

Effects of physical activity on the link between PGC-1a and FNDC5 in muscle, circulating Ιrisin and UCP1 of white adipocytes in humans: A systematic reviewSemantic proximity Read ↗

Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humansSemantic proximity Read ↗

Role and Functions of Irisin: A Perspective on Recent Developments and Neurodegenerative DiseasesSemantic proximity Read ↗

Association of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations.Semantic proximity Read ↗

Obesity and its Association with Irisin Level Among Individuals with FNDC5/Irisin Gene Variants RS16835198 and RS726344.Semantic proximity Read ↗

Fibronectin Type III Domain-Containing Protein 5 rs3480 A>G Polymorphism, Irisin, and Liver Fibrosis in Patients With Nonalcoholic Fatty Liver Disease.Semantic proximity Read ↗

Genetic Variants in the Activation of the Brown-Like Adipocyte Pathway and the Risk for Severe Obesity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.