Article
Association of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations.
International journal of obesity (2005) - 1 Feb 2016
Ebert T, Kralisch S, Wurst U, Scholz M, Stumvoll M, Kovacs P, Fasshauer M, Tönjes A
Abstract excerpt
BACKGROUND/OBJECTIVES: Irisin has been suggested as a novel myokine with beneficial effects in rodents. However, previous data in humans showed conflicting results regarding its association with metabolic phenotypes and regulation of secretion. Furthermore, although an association of rs726344 in FNDC5 (fibronectin type III domain containing 5) coding for irisin with insulin sensitivity was reported, the effects...
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