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Article

SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects.

Lipids in health and disease - 11 Mar 2016

Al-Daghri Nasser M, Mohammed Abdul Khader, Al-Attas Omar S, Amer Osama E, Clerici Mario, Alenad Amal, Alokail Majed S

Abstract excerpt

BACKGROUND: Irisin is a recently identified myokine that plays an important role in preventing obesity and insulin resistance. We investigated whether the common FNDC5 (irisin precursor) gene variants influence susceptibility to obesity and type 2 diabetes (T2D) and verified the impact of FNDC5 gene variants on serum irisin levels, glucose and lipid metabolism in a Saudi population. METHODS: Genomic DNA from 814...

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Source

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Identifiers

PMID: 26968837
DOI: 10.1186/s12944-016-0224-5
PMCID: PMC4788945

Genes

FNDC5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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