Article
A miR-570 binding site polymorphism in the B7-H1 gene is associated with the risk of gastric adenocarcinoma.
Human genetics - 1 Jun 2013
Wang Weipeng, Li Fang, Mao Yong, Zhou Huan, Sun Jing, Li Rui, Liu Cuiping, Chen Weichang, Hua Dong, Zhang Xueguang
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in putative microRNA (miRNA) target sites (miRSNPs) could affect the binding of miRNA with the target and contribute to the susceptibility of human cancers. However, the role of miRSNPs in gastric cancer susceptibility remains largely unknown. Since the over-expression of B7-H1 protein has been reported to be closely related to disease progression of gastric cancer, we...
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