Article
A functional variant at miR-24 binding site in B7-H2 alters susceptibility to gastric cancer in a Chinese Han population.
Molecular immunology - 1 Nov 2013
Yang Panpan, Tang Rong, Zhu Jianjie, Zou Lingting, Wu Ruirong, Zhou Huan, Mao Yong, Li Rui, Hua Dong, Wang Weipeng, Zhang Hongjian
Abstract excerpt
A number of single nucleotide polymorphisms (SNPs) within the 3'-UTR of genes have been proved to be contributed to the risk of cancers. Here, we determined an SNP rs4819388 in the 3'-UTR of B7-H2 gene in 183 gastric cancer patients and 348 healthy controls by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Statistical analysis results showed that the rs4819388...
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