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Article

The MLH1 2101C>A (Q701K) variant increases the risk of gastric cancer in Chinese males.

BMC gastroenterology - 3 Dec 2011

Zhi Wenxian, Xue Binshuang, Wang Lifeng, Xiao Nong, He Qiong, Wang Yaping, Fan Yimei

Abstract excerpt

BACKGROUND: Gastric cancer is one of the most common cancers affecting East Asians, and MLH1 could play a critical role during tumorigenesis in this condition. METHODS: Samples from 236 Chinese patients suffering from gastric cancer were screened for MLH1 germline mutations. Carrier frequencies of the mutations were compared between gastric cancer patients and 240 cancer-free controls. Bioinformatic analysis was...

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Source

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Identifiers

PMID: 22136435
DOI: 10.1186/1471-230X-11-133
PMCID: PMC3275522

Genes

MLH1
MSH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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