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Article

The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer.

Mutation research - 30 Sept 2010

Huang Yu-Jing, Niu Jiangong, Liu Zhensheng, Wang Li-E, Sturgis Erich M, Wei Qingyi

Abstract excerpt

Insulin-like growth factor binding protein 7 (IGFBP7) functions mostly independent of the IGF signaling pathway and acts as a tumor suppressor in multiple cancers, but roles of IGFBP7 genetic variants in cancer remains unknown. In a hospital-based study of 1065 patients with squamous cell carcinoma of head and neck (SCCHN) and 1112 cancer-free controls of non-Hispanic whites, we investigated associations between...

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Source

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Identifiers

PMID: 20599521
DOI: 10.1016/j.mrgentox.2010.06.012
PMCID: PMC2939148

Genes

IGFBP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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