Article
Variant SNPs at the microRNA complementary site in the B7‑H1 3'‑untranslated region increase the risk of non‑small cell lung cancer.
Molecular medicine reports - 1 Sept 2017
Du Wenwen, Zhu Jianjie, Chen Yanbin, Zeng Yuanyuan, Shen Dan, Zhang Nan, Ning Weiwei, Liu Zeyi, Huang Jian-An
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in microRNA‑binding sites located in the 3'‑untranslated region (UTR) of target genes can have an effect on the interaction of microRNA‑mediated regulation, which results in changes in the expression levels of target genes ultimately associated with cancer risk and patient prognosis. However, the role of SNPs at the 3'‑UTR of B7‑H1 in the susceptibility of non‑small cell...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
