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Article

A complex selection signature at the human AVPR1B gene.

BMC evolutionary biology - 1 Jun 2009

Cagliani Rachele, Fumagalli Matteo, Pozzoli Uberto, Riva Stefania, Cereda Matteo, Comi Giacomo P, Pattini Linda, Bresolin Nereo, Sironi Manuela

Abstract excerpt

BACKGROUND: The vasopressin receptor type 1b (AVPR1B) is mainly expressed by pituitary corticotropes and it mediates the stimulatory effects of AVP on ACTH release; common AVPR1B haplotypes have been involved in mood and anxiety disorders in humans, while rodents lacking a functional receptor gene display behavioral defects and altered stress responses. RESULTS: Here we have analyzed the two exons of the gene and...

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Source

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Identifiers

PMID: 19486526
DOI: 10.1186/1471-2148-9-123
PMCID: PMC2700802

Genes

AVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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