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Article

The IRS1 rs2943641 variant and risk of future cancer among morbidly obese individuals.

The Journal of clinical endocrinology and metabolism - 1 Apr 2013

Maglio Cristina, Ericson Ulrika, Burza Maria Antonella, Mancina Rosellina Margherita, Pirazzi Carlo, Assarsson Johanna Andersson, Sjöholm Kajsa, Baroni Marco Giorgio, Svensson Per-Arne, Montalcini Tiziana, Pujia Arturo, Sjöström Lars, Wiklund Olov, Carlsson Lena M S, Borén Jan, Orho-Melander Marju, Romeo Stefano

Abstract excerpt

CONTEXT: Obesity and insulin resistance are risk factors for cancer development. The IRS1 rs2943641 genetic variant has been widely associated with insulin resistance. OBJECTIVE: The aim of the study was to examine whether the IRS1 rs2943641 associates with cancer incidence in obese individuals. DESIGN, SETTING AND PATIENTS: The IRS1 rs2943641 was genotyped in participants from the Swedish Obese Subjects (SOS)...

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Source

Identifiers

PMID: 23418314
DOI: 10.1210/jc.2012-2831

Genes

IRS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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