Article
High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery.
Obesity (Silver Spring, Md.) - 1 Aug 2011
Still Christopher D, Wood G Craig, Chu Xin, Erdman Robert, Manney Christina H, Benotti Peter N, Petrick Anthony T, Strodel William E, Mirshahi Uyenlinh L, Mirshahi Tooraj, Carey David J, Gerhard Glenn S
Abstract excerpt
Genome-wide association and linkage studies have identified multiple susceptibility loci for obesity. We hypothesized that such loci may affect weight loss outcomes following dietary or surgical weight loss interventions. A total of 1,001 white individuals with extreme obesity (BMI >35 kg/m(2)) who underwent a preoperative diet/behavioral weight loss intervention and Roux-en-Y gastric bypass surgery were...
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