Article
Association of morbid obesity with FTO and INSIG2 allelic variants.
Archives of surgery (Chicago, Ill. : 1960) - 1 Mar 2008
Chu Xin, Erdman Robert, Susek Meghan, Gerst Heather, Derr Kimberly, Al-Agha Mouna, Wood G Craig, Hartman Christina, Yeager Stephanie, Blosky Mary Ann, Krum Wanda, Stewart Walter F, Carey David, Benotti Peter, Still Christopher D, Gerhard Glenn S
Abstract excerpt
OBJECTIVE: To determine whether 2 single nucleotide polymorphisms (SNPs) in the obesity genes the fat mass and obesity associated gene (FTO) and the insulin induced gene 2 (INSIG2) are associated with class III, or morbid, obesity in patients undergoing bariatric weight loss operations. DESIGN: Retrospective analysis of genotype and clinical data. SETTING: Large rural tertiary care health system. PATIENTS: A...
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