Article
Differential expression of insulin receptor substrate-1(IRS-1) in visceral and subcutaneous adipose depots of morbidly obese subjects undergoing bariatric surgery in a tertiary care center in north India; SNP analysis and correlation with metabolic profile.
Diabetes & metabolic syndrome - 1 Jan 2000
Sharma Mukti, Aggarwal Sandeep, Nayar Umakant, Vikram Naval Kishore, Misra Anoop, Luthra Kalpana
Abstract excerpt
BACKGROUND: /aim: Abdominal obesity and associated metabolic consequences are a burgeoning problem in Asian Indians and studying their genetic predisposition is important. This study is aimed at assessing variations in Insulin receptor substrate-1 (IRS-1), its expression at regional fat-depots (visceral and subcutaneous) in morbidly obese patients, and correlation with genotype-phenotype traits. METHODS: Gene...
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