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Article

Association between FTO rs9939609 genotype and breast cancer risk after bariatric surgery in the Swedish Obese Subjects study.

Scientific reports - 6 May 2026

Langegård Elin, Kristensson Felipe M, Andersson-Assarsson Johanna C, Peltonen Markku, Svensson Per-Arne, Jacobson Peter, Ahlin Sofie, Sjöholm Kajsa, Carlsson Lena M S, Taube Magdalena

Abstract excerpt

The FTO rs9939609 SNP has been linked to higher BMI, insulin resistance, and breast cancer risk. Weight loss by bariatric surgery lowers breast cancer risk, particularly in women with baseline hyperinsulinemia, but it is unclear whether this effect varies by FTO genotype. In the Swedish Obese Subjects (SOS) study, 2596 women with severe obesity were followed for a median of 23.9 years to examine breast cancer...

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Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Bariatric Surgery
Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 42091990
DOI: 10.1038/s41598-026-51884-2
PMCID: PMC13149690

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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