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Article

Interleukin-23 receptor (IL-23R) gene polymorphisms in acquired aplastic anemia.

Annals of hematology - 1 Jul 2009

Takaku Tomoiku, Calado Rodrigo T, Kajigaya Sachiko, Young Neal S

Abstract excerpt

Acquired aplastic anemia (AA) is a rare disease with a complex pathogenesis. In most cases, T cell-mediated immune destruction of hematopoietic cells results in peripheral blood pancytopenia and bone marrow hypoplasia. A subset of the heterodimeric interleukin-23 receptor gene (IL-23R) is significantly associated with autoimmune-mediated diseases. To examine whether IL-23R single nucleotide polymorphisms (SNPs)...

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Share to Anemia, Aplastic
Share to Autoimmunity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Interleukin-23

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Share to Polymorphism, Genetic

Share to Receptors, Interleukin

Source

Open in PubMed Open full text

Identifiers

PMID: 19165485
DOI: 10.1007/s00277-008-0666-6
PMCID: PMC3438141

Variants

rs11209026
rs11465797
rs41313262

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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