Article
Interleukin-23 Receptor Gene Variants in Acute Lymphoblastic Leukemia and Their Relation to Prognostic Factors.
Iranian journal of immunology : IJI - 1 Mar 2017
Zareinejad Mohammadrasul, Samiei Afshin, Valibeigi Behnaz, Gholami Tahereh, Zareifar Soheila, Amirghofran Zahra
Abstract excerpt
BACKGROUND: Interleukin (IL)-23 has an important role in tumor immune regulation. OBJECTIVE: To investigate the possible association of interleukin-23 receptor (IL23R) gene variants rs1884444, rs10889677 and rs11209026 with development of acute lymphoblastic leukemia (ALL). METHODS: The IL23R variants were studied in 164 ALL patients and compared to 175 healthy controls by polymerase chain reaction-restriction...
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