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Association of interleukin-23 receptor gene polymorphisms with risk of ovarian cancer.

Cancer genetics and cytogenetics - 15 Jan 2010

Zhang Zhu, Zhou Bin, Zhang Jian, Chen Yue, Lai Ting, Yan Li, Liang Ailing, Li Yi, Wang Yanyun, Chen Yu, Zhang Lin, Xi Ming-Rong

Abstract excerpt

Among gynecological malignancies, ovarian cancer is the leading cause of death. The overall 5-year survival rate remains poor, and the pathogenesis is unknown. The interleukin-23 receptor (IL23R) is known to be critically involved in the carcinogenesis of different malignant tumors. To assess the role of IL23R in ovarian cancer, we conducted a study to investigate the polymorphisms of the IL23R gene in 96 Han...

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PMID: 20082850
DOI: 10.1016/j.cancergencyto.2009.09.006

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