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Article

Functional IL-23R rs10889677 genetic polymorphism and risk of multiple solid tumors: a meta-analysis.

PloS one - 1 Jan 2013

Zhou Shanliang, Ruan Yueqin, Yu Hongchen, Chen Yunzhi, Yao Yongjun, Ma Yanhui, Gao Yan

Abstract excerpt

Interleukin-23 receptor (IL23R) can interact with IL-23 and, thus, is involved in the T-helper 17 (Th17) cell-mediated inflammatory process as well as tumorigenesis. Recently, a functional single nucleotide polymorphism (SNP) rs10889677 has been identified in the 3'-untranslated region of IL-23R. It has been showed that the rs10889677AC SNP could increase the binding affinity of microRNA let-7f and downregulate...

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Identifiers

PMID: 24278297
DOI: 10.1371/journal.pone.0080627
PMCID: PMC3835319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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