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Article

IL-23R polymorphisms, HBV infection, and risk of hepatocellular carcinoma in a high-risk Chinese population.

Journal of gastroenterology - 1 Jan 2013

Xu Yan, Liu Yao, Pan Shandong, Liu Li, Liu Jibin, Zhai Xiangjun, Shen Hongbing, Hu Zhibin

Abstract excerpt

BACKGROUND: The interleukin-23 receptor (IL-23R) plays an important role in the T-helper 17 cell-mediated inflammatory process and is also involved in tumor immune surveillance, which may be linked to carcinogenesis in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). In this study, we hypothesized that potentially functional genetic variants of the IL-23R gene may modify HCC risk. METHODS: We...

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Source

Identifiers

PMID: 22735941
DOI: 10.1007/s00535-012-0620-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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