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Article

A nonsynonymous polymorphism in IL23R gene is associated with risk of gastric cancer in a Chinese population.

Molecular carcinogenesis - 1 Oct 2010

Chen Jianjian, Lu Yan, Zhang Hanze, Ding Yanbing, Ren Chuanli, Hua Zhaolai, Zhou Yan, Deng Bin, Jin Guangfu, Hu Zhibin, Xu Yaochu, Shen Hongbing

Abstract excerpt

Interleukin-23 receptor (IL-23R) is a key element in T helper (Th)17 cell-mediated inflammatory process, which plays an important role in pathogenesis of gastric cancer. Genetic variants of IL-23R have been identified as the predisposing factors for immunopathologic process. In this study, we hypothesized that the functional genetic variants of IL-23R gene may modify the risk of gastric cancer. To test this...

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Identifiers

PMID: 20607725
DOI: 10.1002/mc.20661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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