Article
A PheWAS approach in studying HLA-DRB1*1501.
Genes and immunity - 1 Apr 2013
Hebbring S J, Schrodi S J, Ye Z, Zhou Z, Page D, Brilliant M H
Abstract excerpt
HLA-DRB1 codes for a major histocompatibility complex class II cell surface receptor. Genetic variants in and around this gene have been linked to numerous autoimmune diseases. Most notably, an association between HLA-DRB1*1501 haplotype and multiple sclerosis (MS) has been defined. Utilizing electronic health records and 4235 individuals within Marshfield Clinic's Personalized Medicine Research Project, a...
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