Article
Association of variably expressed KIR3dl1 alleles with psoriatic disease.
Clinical rheumatology - 1 Oct 2017
Berinstein Jeffrey, Pollock Remy, Pellett Fawnda, Thavaneswaran Arane, Chandran Vinod, Gladman Dafna D
Abstract excerpt
The purpose of this study is to examine the genetic interaction of variably expressed killer cell immunoglobulin-like receptor (KIR) 3DL1 alleles with their cognate ligand, human leukocyte antigen (HLA)-Bw4, in susceptibility to psoriatic disease (PsD). A novel allelic typing system was developed to differentiate KIR3DL1 alleles (*High, *Low, *Null expression, and 3DS1), in PsD patients, including those with...
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