Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The challenges, advantages and future of phenome-wide association studies.

Immunology - 1 Feb 2014

Hebbring Scott J

Abstract excerpt

Over the last decade, significant technological breakthroughs have revolutionized human genomic research in the form of genome-wide association studies (GWASs). GWASs have identified thousands of statistically significant genetic variants associated with hundreds of human conditions including many with immunological aetiologies (e.g. multiple sclerosis, ankylosing spondylitis and rheumatoid arthritis)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome-Wide Association Study
Share to Genotype
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inflammasome and immune disorders

Share to International Classification of Diseases

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Systemic Lupus Erythematosus Research

Source

Open in PubMed Open full text

Identifiers

PMID: 24147732
DOI: 10.1111/imm.12195
PMCID: PMC3904236

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The challenges, advantages and future of phenome-wide association studies.PMID 24147732Read ↗

Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases.Semantic proximity Read ↗

Maturation and application of phenome-wide association studies.Semantic proximity Read ↗

R PheWAS: data analysis and plotting tools for phenome-wide association studies in the R environment.Semantic proximity Read ↗

Phenome-wide association study maps new diseases to the human major histocompatibility complex region.Semantic proximity Read ↗

Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.Semantic proximity Read ↗

Phenome-Wide Association Studies as a Tool to Advance Precision Medicine.Semantic proximity Read ↗

A survey of genome-wide association studies, polygenic scores and UK Biobank highlights resources for autoimmune disease genetics.Semantic proximity Read ↗

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations.Semantic proximity Read ↗

Comparison of phenomic profiles in the All of Us Research Program against the US general population and the UK Biobank.Semantic proximity Read ↗

Phenome-wide HLA association landscape of 235,000 Finnish biobank participantsSemantic proximity Read ↗

A global atlas of genetic associations of 220 deep phenotypesSemantic proximity Read ↗

[Research progress in the methodology used in phenome-wide association studies].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.