Article
Field Synopsis and Re-analysis of Systematic Meta-analyses of Genetic Association Studies in Multiple Sclerosis: a Bayesian Approach.
Molecular neurobiology - 1 Jul 2018
Park Jae Hyon, Kim Joo Hi, Jo Kye Eun, Na Se Whan, Eisenhut Michael, Kronbichler Andreas, Lee Keum Hwa, Shin Jae Il
Abstract excerpt
To provide an up-to-date summary of multiple sclerosis-susceptible gene variants and assess the noteworthiness in hopes of finding true associations, we investigated the results of 44 meta-analyses on gene variants and multiple sclerosis published through December 2016. Out of 70 statistically significant genotype associations, roughly a fifth (21%) of the comparisons showed noteworthy false-positive rate...
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