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Article

Point mutations in the Rpb9-homologous domain of Rpc11 that impair transcription termination by RNA polymerase III.

Nucleic acids research - 1 Aug 2011

Iben James R, Mazeika Julie K, Hasson Sam, Rijal Keshab, Arimbasseri Aneeshkumar G, Russo Amy N, Maraia Richard J

Abstract excerpt

RNA polymerase III recognizes and pauses at its terminator, an oligo(dT) tract in non-template DNA, terminates 3' oligo(rU) synthesis within this sequence, and releases the RNA. The pol III subunit Rpc11p (C11) mediates RNA 3'-5' cleavage in the catalytic center of pol III during pausing. The amino and carboxyl regions of C11 are homologous to domains of the pol II subunit Rpb9p, and the pol II elongation and RNA...

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Identifiers

PMID: 21450810
DOI: 10.1093/nar/gkr182
PMCID: PMC3152337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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