Article
Mutations in a conserved region of RNA polymerase II influence the accuracy of mRNA start site selection.
Molecular and cellular biology - 1 Nov 1991
Hekmatpanah D S, Young R A
Abstract excerpt
A sensitive phenotypic assay has been used to identify mutations affecting transcription initiation in the genes encoding the two large subunits of Saccharomyces cerevisiae RNA polymerase II (RPB1 and RPB2). The rpb1 and rpb2 mutations alter the ratio of transcripts initiated at two adjacent star...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Binding Sites
- Blotting, Northern
- Drosophila melanogaster
- Genes, Recessive
- Genotype
- Mice
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phenotype
- Plasmids
- RNA Polymerase II
- RNA, Fungal
- RNA, Messenger
- Saccharomyces cerevisiae
- Sequence Homology, Nucleic Acid