Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common genetic variants in peroxisome proliferator-activated receptor-γ (PPARG) and type 2 diabetes risk among Women's Health Initiative postmenopausal women.

The Journal of clinical endocrinology and metabolism - 1 Mar 2013

Chan Kei Hang K, Niu Tianhua, Ma Yunsheng, You Nai-chieh Y, Song Yiqing, Sobel Eric M, Hsu Yi-Hsiang, Balasubramanian Raji, Qiao Yongxia, Tinker Lesley, Liu Simin

Abstract excerpt

CONTEXT: Peroxisome proliferator-activated receptor-γ (PPARG) plays a pivotal role in adipogenesis and glucose homeostasis. OBJECTIVE: We investigated whether PPARG gene variants were associated with type 2 diabetes (T2D) risk in the multiethnic Women's Health Initiative (WHI). RESEARCH DESIGN AND METHODS: We assessed PPARG single-nucleotide polymorphisms (SNPs) in a case-control study nested in the prospective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipogenesis
Share to Asian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black or African American

Share to Blood Glucose

Share to Hispanic or Latino

Share to Multivariate Analysis

Share to Postmenopause

Share to PPAR gamma

Source

Open in PubMed Open full text

Identifiers

PMID: 23386649
DOI: 10.1210/jc.2012-3644
PMCID: PMC3590470

Genes

PPARG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common genetic variants in peroxisome proliferator-activated receptor-γ (PPARG) and type 2 diabetes risk among Women's Health Initiative postmenopausal women.PMID 23386649Read ↗

The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis.Semantic proximity Read ↗

The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences.Semantic proximity Read ↗

Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.Semantic proximity Read ↗

Association between PPAR-γ (rs1801282) polymorphism and susceptibility to obesity and type 2 diabetes mellitus: a meta-analysis with trial sequential analysisSemantic proximity Read ↗

PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pro12Ala still remains as the strongest predictor.Semantic proximity Read ↗

PPARG (Pro12Ala) genetic variant and risk of T2DM: a systematic review and meta-analysis.Semantic proximity Read ↗

Metabolic Biomarkers in Adults with Type 2 Diabetes: The Role of PPAR-γ2 and PPAR-β/δ Polymorphisms.Semantic proximity Read ↗

Genetic polymorphisms in peroxisome proliferator-activated receptor delta associated with obesity.Semantic proximity Read ↗

The Effect Sizes of PPARγ rs1801282, FTO rs9939609, and MC4R rs2229616 Variants on Type 2 Diabetes Mellitus Risk among the Western Saudi Population: A Cross-Sectional Prospective Study.Semantic proximity Read ↗

Association of the rs3856806 Polymorphism in the PPARG Gene with Type 2 Diabetes Mellitus: A Meta-Analysis of 11,811 Individuals.Semantic proximity Read ↗

Evaluation of the association between the PPARGC1A genetic polymorphisms and type 2 diabetes in Han Chinese population.Semantic proximity Read ↗

Implications of critical PPARγ2, ADIPOQ and FTO gene polymorphisms in type 2 diabetes and obesity-mediated susceptibility to type 2 diabetes in an Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.