Article
Implications of critical PPARγ2, ADIPOQ and FTO gene polymorphisms in type 2 diabetes and obesity-mediated susceptibility to type 2 diabetes in an Indian population.
Molecular genetics and genomics : MGG - 1 Feb 2016
Phani Nagaraja M, Vohra Manik, Rajesh Somyasree, Adhikari Prabha, Nagri Shivashankara K, D'Souza Sydney C, Satyamoorthy Kapaettu, Rai Padmalatha S
Abstract excerpt
Peroxisome proliferator-activated receptors (PPARγ), adiponectin (ADIPOQ) and fat mass and obesity-associated gene (FTO) have been reported as a key candidate genes for obesity, type 2 diabetes (T2D) susceptibility and insulin resistance, and we hypothesize that in the background of obesity, the effect of PPARγ2 (rs1801282), ADIPOQ (rs16861194) and FTO (rs9939609) variant could potentially influence T2D...
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