Article
Evaluation of the association between the PPARGC1A genetic polymorphisms and type 2 diabetes in Han Chinese population.
Diabetes research and clinical practice - 1 Dec 2009
Zhu Shuying, Liu Yang, Wang Xin, Wu Xiaopan, Zhu Xilin, Li Jingyun, Ma Juan, Gu Harvest F, Liu Ying
Abstract excerpt
AIMS: The peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PPARGC1A) is a transcriptional factor that regulates the genes involved in energy metabolism. Single nucleotide polymorphisms (SNPs) in the PPARGC1A gene have been conflictingly reported to be associated with type 2 diabetes (T2D) in several populations. The present study aimed to evaluate the association of PPARGC1A genetic...
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