Article
The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis.
American journal of epidemiology - 15 Mar 2010
Gouda Hebe N, Sagoo Gurdeep S, Harding Anne-Helen, Yates Jan, Sandhu Manjinder S, Higgins Julian P T
Abstract excerpt
The peroxisome proliferator-activated receptor-gamma gene (PPARG) has been implicated in the etiology of type 2 diabetes mellitus and has been investigated in numerous epidemiologic studies. In this Human Genome Epidemiology review, the authors assessed this relation in an updated meta-analysis of 60 association studies. Electronic literature searches were conducted on September 14, 2009. Population-based cohort,...
Topics
- Diabetes Mellitus, Type 2
- Gene Frequency
- Genetic Heterogeneity
- Genetic Predisposition to Disease
- Humans
- PPAR gamma
- Polymorphism, Genetic
- Regression Analysis